Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607151 | 0.83 | FAAH (0.45) | FAAH | |
| SCHEMBL2718216 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL9500228 | 0.81 | AOC3 (0.56) | CASP3SENP7SENP8SENP6CYP17A1 | |
| SCHEMBL19307951 | 0.80 | RXFP1 (0.54) | RXFP1CASP3SENP7SENP8SENP6 | |
| SCHEMBL615718 | 0.79 | AOC3 (0.61) | CYP17A1AOC3ALDH1A1MAPT | |
| SCHEMBL2517919 | 0.79 | AOC3 (0.61) | CYP17A1AOC3ALDH1A1MAPT | |
| SCHEMBL3930580 | 0.79 | AOC3 (0.61) | CYP17A1AOC3ALDH1A1MAPT | |
| SCHEMBL2277500 | 0.78 | KDM1A (0.44) | CYP11B1FAAHIDO1TDO2CYP11B2 | |
| SCHEMBL2270298 | 0.78 | KDM1A (0.44) | CYP11B1FAAHIDO1TDO2CYP11B2 | |
| SCHEMBL2277499 | 0.78 | KDM1A (0.44) | CYP11B1FAAHIDO1TDO2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |