Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607431 | 0.83 | RXFP1 (0.51) | FAAH | |
| SCHEMBL2277499 | 0.82 | KDM1A (0.44) | FAAHSCN9APDE2AKCNH2TRPV3 | |
| SCHEMBL2270298 | 0.82 | KDM1A (0.44) | FAAHSCN9APDE2AKCNH2TRPV3 | |
| SCHEMBL2277500 | 0.82 | KDM1A (0.44) | FAAHSCN9APDE2AKCNH2TRPV3 | |
| SCHEMBL19237526 | 0.82 | ALDH1A1 (0.46) | SCN9APDE2ASCN10AKCNH2SCN5A | |
| SCHEMBL9607474 | 0.82 | PDE2A (0.42) | SCN9APDE2ASCN10A | |
| SCHEMBL4542016 | 0.81 | PDE2A (0.54) | PDE2A | |
| SCHEMBL9607465 | 0.79 | PRMT6 (0.49) | FAAHSCN9APDE2ASCN10AKCNH2 | |
| SCHEMBL22585573 | 0.77 | LMNA (0.38) | PDE2A | |
| SCHEMBL2056330 | 0.77 | SMN1; SMN2 (0.54) | SCN10ASCN5ACYP1A2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |