Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063316 | 0.82 | TDP1 (0.48) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL4027568 | 0.80 | TDP1 (0.47) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL2125436 | 0.80 | MAOA (0.61) | MAOAMAOBGPR3CYP1A2ALDH1A1 | |
| SCHEMBL2712314 | 0.80 | MAOA (0.61) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL30774177 | 0.80 | MAOA (0.61) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL12877168 | 0.77 | MAOA (0.57) | MAOAMAOBGPR3CYP1A2ALDH1A1 | |
| SCHEMBL12490195 | 0.77 | MAOA (0.57) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL28494617 | 0.77 | MAOA (0.57) | MAOAMAOBTDP1GPR3CYP1A2 | |
| SCHEMBL2123575 | 0.76 | PDE10A (0.58) | MAOAMAOBTDP1ALDH1A1KDM4E | |
| SCHEMBL455949 | 0.74 | MAOA (1.00) | MAOAMAOBTDP1GPR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |