SCHEMBL455949

SCHEMBL455949

Clc1c2ccccc2nc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 1.00
MAOB P27338 1/20 1.00
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 5/20 0.56
GLA P06280 4/20 0.56
HPGD P15428 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
CASP1 P29466 2/20 0.56
CASP7 P55210 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HSD17B10 Q99714 2/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CHRM1 P11229 1/20 0.56
NQO2 P16083 1/20 0.56
DRD1 P21728 1/20 0.56
ACHE P22303 1/20 0.56
SLC6A2 P23975 1/20 0.56
ADRA1A P35348 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27889436 1.00 MAOA (1.00) MAOAMAOBKDM4EALDH1A1GLA
Hydrochloric Acid SCHEMBL28400797 0.97 MAOA (0.95) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL15124839 0.91 MAOA (0.82) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL11780381 0.87 MAOA (0.75) MAOAMAOBKDM4EALDH1A1HPGD
SCHEMBL7533781 0.85 MAOA (0.72) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL9709249 0.85 MAOA (0.72) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL15131691 0.84 MAOA (0.73) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL6679033 0.82 MAOA (0.70) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL15673439 0.82 MAOA (0.67) MAOAMAOBKDM4EALDH1A1GLA
SCHEMBL9593514 0.82 MAOA (0.67) MAOAMAOBKDM4EALDH1A1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801596-B Photosensitive polyimide resin composition and preparation method and application thereof 深圳先进电子材料国际创新研究院 2025-04-25 CN claimed
CN-118994006-A Fatty acid-sensitive fluorescent life probe, preparation method and biological application 安徽大学 2024-11-22 CN claimed
CN-117003787-A Selective silicon-based-arylation method of olefin compound 南京大学 2023-11-07 CN claimed
CN-115710226-A Preparation method of 9-chloroacridine 郑州原理生物科技有限公司 2023-02-24 CN claimed
CN-110804050-B Synthesis of selenazole fluorescent dye compound and performance research thereof 福建医科大学 2022-11-08 CN claimed
CN-115286574-A BLVRB enzyme function inhibitor and preparation method and application thereof 吉林医药学院 2022-11-04 CN claimed
CN-110804050-A Synthesis of selenazole fluorescent dye compound and performance research thereof 福建医科大学 2020-02-18 CN claimed
CN-108640873-A A kind of imines acridine derivatives fluorescence probe and preparation method thereof and detection MORAb-3-1 antibody applications 福建医科大学 2018-10-12 CN claimed
CN-104961801-B A kind of synthesis and application of antibacterial polypeptide conjugate and its dimer with Mutiple Targets 兰州大学 2018-01-19 CN claimed
CN-104402818-B A kind of compound or pharmaceutically acceptable salt thereof with tumour response release medicine and preparation, application 河南大学 2016-07-06 CN claimed
WO-1996000392-A1 PREPARATION OF DERIVATIZED 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND SIGNAL SOLUTIONS KATSILOMETES GEORGE W (US) 1996-01-04 WO claimed
EP-0220604-B1 Electrophotographic-recording material HOECHST AG (DE) 1994-03-30 EP claimed
WO-1993023049-A1 3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE DERIVATIVES AS ANTICANCER AGENTS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1993-11-25 WO claimed
US-4818653-A ANTHRACENE OR ACRIDINE WITH ELECTRON-ATTRACTING SUBSTITUENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-04 US claimed
EP-0220604-A2 Electrophotographic-recording material HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-06 EP claimed
EP-0039224-B1 COMPOUND HAVING ANTITUMOUR PROPERTIES DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1984-06-27 EP claimed
EP-0025705-B1 COMPOUNDS HAVING ANTITUMOUR PROPERTIES, PROCESS FOR THEIR PREPARATION, THESE COMPOUNDS FOR USE AS ANTITUMOUR AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1983-06-22 EP claimed
EP-0039224-A2 Compound having antitumour properties DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1981-11-04 EP claimed
EP-0025705-A1 Compounds having antitumour properties, process for their preparation, these compounds for use as antitumour agents and pharmaceutical compositions containing them DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1981-03-25 EP claimed
US-4258191-A STARTING WITH 4-BUTYRYLAMINO-3-METHOXY-NITROBENZENE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) 1981-03-24 US claimed