Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | ACACA | Q13085 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607474 | 0.85 | PDE2A (0.42) | ALDH1A1ACACBACACA | |
| SCHEMBL12808386 | 0.84 | MEN1 (0.53) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL14997990 | 0.80 | KDM4E (0.58) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL14831238 | 0.78 | KDM4E (0.59) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27295625 | 0.78 | KDM4E (0.59) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16762977 | 0.77 | LMNA (0.42) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22585573 | 0.75 | LMNA (0.38) | L3MBTL1ALDH1A1 | |
| SCHEMBL12967186 | 0.74 | MEN1 (0.58) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1978021 | 0.74 | LMNA (0.60) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL2632364 | 0.74 | LMNA (0.60) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |