Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22585573 | 0.86 | LMNA (0.38) | PDE2ALMNAPDE3APDE10AALDH1A1 | |
| SCHEMBL9607482 | 0.85 | MEN1 (0.51) | ACACBACACAALDH1A1 | |
| SCHEMBL9607151 | 0.82 | FAAH (0.45) | PDE2ASCN9ASCN10A | |
| SCHEMBL4542016 | 0.81 | PDE2A (0.54) | PDE2ALMNAALDH1A1 | |
| SCHEMBL22585575 | 0.76 | L3MBTL1 (0.50) | PDE2ALMNASCN9A | |
| SCHEMBL7989179 | 0.75 | PDE4A (0.37) | LMNASCN9ALIPESCN10A | |
| SCHEMBL9607167 | 0.75 | PDE2A (0.48) | PDE2ALMNAALDH1A1 | |
| SCHEMBL2269736 | 0.74 | LMNA (0.46) | LMNASCN9ALIPE | |
| SCHEMBL9607063 | 0.74 | LMNA (0.53) | LMNALIPE | |
| SCHEMBL16762977 | 0.74 | LMNA (0.42) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |