Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607542 | 1.00 | GABRB1 (0.57) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL1954379 | 0.89 | GABRB1 (0.56) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL56893 | 0.89 | GABRB1 (0.56) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL56959 | 0.89 | GABRB1 (0.56) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL20721134 | 0.87 | GABRB1 (0.55) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL15045485 | 0.86 | HTT (0.54) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL13132826 | 0.86 | HTT (0.54) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL13051349 | 0.86 | MAPT (0.60) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL90008 | 0.86 | MAPT (0.57) | GABRB1GABRB2MAPTCTSKCTSS | |
| SCHEMBL90081 | 0.86 | MAPT (0.57) | GABRB1GABRB2MAPTCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | MERCK & CO., INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | CNR1, CNR2, FAAH | GABRB1 115/4885GABRB2 170/4885MAPT 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.