Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291326 | 0.86 | SIRT2 (0.37) | TSHRPOLBLMNA | |
| SCHEMBL12679288 | 0.76 | TSHR (0.32) | TSHRPOLBLMNA | |
| SCHEMBL10304537 | 0.74 | SIRT2 (0.32) | — | |
| SCHEMBL92282 | 0.72 | — | — | |
| SCHEMBL21944471 | 0.72 | — | — | |
| SCHEMBL17771193 | 0.71 | — | — | |
| SCHEMBL13900140 | 0.71 | PRKCA (0.32) | — | |
| SCHEMBL12355562 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL15477335 | 0.70 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL5919629 | 0.69 | PRKCA (0.33) | TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944679-A | Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks | THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) | 1976-03-16 | — | — | US | claimed |
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | MERCK & CO., INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-7300948-B2 | Alkynyl compounds as non nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20070066579-A1 | 5-androsten-3beta-ol steroid intermediates and processs for their preparation | WHITE MICHAEL J | 2007-03-22 | — | — | US | disclosed |
| US-3944679-A | Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks | THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066579-A1 | 5-androsten-3beta-ol steroid intermediates and processs for their preparation | CYP17A1, NR5A1, HSD3B2 | TSHR 825/4885POLB 1393/4885IDO1 3070/4885 |
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | CNR1, CNR2, FAAH | TSHR 768/4885POLB 2185/4885IDO1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.