Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232809 | 0.99 | LMNA (0.45) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL10051163 | 0.94 | LMNA (0.49) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12841342 | 0.93 | NPC1 (0.41) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL762322 | 0.92 | LMNA (0.56) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9607798 | 0.91 | LMNA (0.47) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12199819 | 0.91 | LMNA (0.46) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13882229 | 0.91 | NPC1 (0.46) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL14363594 | 0.90 | LMNA (0.46) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12198492 | 0.89 | LMNA (0.46) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9965882 | 0.89 | LMNA (0.46) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120133882-A1 | LIQUID CRYSTAL FILM AND OPTICAL ELEMENT PRODUCED USING SAME | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |