SCHEMBL10051163

SCHEMBL10051163

CCC1(COCCCCOc2ccc(C(=O)Oc3ccc(OC(=O)c4ccc(OCCCCOCC5(CC)COC5)cc4)cc3)cc2)COC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.49
NPC1 O15118 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
NFKB1 P19838 3/20 0.48
NFKB2 Q00653 3/20 0.48
RELA Q04206 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
PRSS1 P07477 1/20 0.46
ACR P10323 1/20 0.46
MAPT P10636 4/20 0.45
KMT2A Q03164 3/20 0.45
POLB P06746 2/20 0.42
TSHR P16473 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607798 0.98 LMNA (0.47) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL16575028 0.96 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL12198492 0.96 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL762322 0.96 LMNA (0.56) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL9965882 0.96 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL13232809 0.94 LMNA (0.45) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL13882229 0.94 NPC1 (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL12199819 0.94 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL9607797 0.94 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL14363594 0.94 LMNA (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1990339-B1 DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM AND LIQUID CRYSTAL DISPLAY UNIT NIPPON OIL CORP (JP) 2012-05-02 EP disclosed
EP-2006351-B1 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM NIPPON OIL CORP (JP) 2011-10-12 EP disclosed
US-7998543-B2 Dioxetane compound, cationically polymerizable composition, optical film, and liquid crystal display device NIPPON OIL CORPORATION (JP) 2011-08-16 US disclosed
US-7998543-B2 Dioxetane compound, cationically polymerizable composition, optical film, and liquid crystal display device NIPPON OIL CORPORATION (JP) 2011-08-16 US disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-20090208673-A1 Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film NIPPON OIL CORPORATION (JP) 2009-08-20 US disclosed
US-20090086140-A1 PHOTO ALIGNMENT FILM AND RETARDATION FILM, AND THEIR APPLICATIONS, AND COMPOSITIONS AND METHODS FOR PRODUCING THEM FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090086140-A1 PHOTO ALIGNMENT FILM AND RETARDATION FILM, AND THEIR APPLICATIONS, AND COMPOSITIONS AND METHODS FOR PRODUCING THEM FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090068379-A1 DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE NIPPON OIL CORPORATION (JP) 2009-03-12 US disclosed
US-20090068379-A1 DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE NIPPON OIL CORPORATION (JP) 2009-03-12 US disclosed
EP-2006351-A2 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2008-12-24 EP disclosed
EP-1990339-A1 DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM AND LIQUID CRYSTAL DISPLAY UNIT Nippon Oil Corporation (JP) 2008-11-12 EP disclosed
US-7416765-B2 Polymerizable liquid crystalline composition and liquid crystal film made from the composition NIPPON OIL CORPORATION (JP) 2008-08-26 US disclosed
US-20070164255-A1 POLYMERIZABLE LIQUID CRYSTALLINE COMPOSITION AND LIQUID CRYSTAL FILM MADE FROM THE COMPOSITION NIPPON OIL CORPORATION (JP) 2007-07-19 US disclosed
US-7244798-B2 (Meth) acrylic compound having an oxetanyl group and liquid crystal film produced by using same NIPPON OIL CORPORATION (JP) 2007-07-17 US disclosed
US-7244798-B2 (Meth) acrylic compound having an oxetanyl group and liquid crystal film produced by using same NIPPON OIL CORPORATION (JP) 2007-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090086140-A1 PHOTO ALIGNMENT FILM AND RETARDATION FILM, AND THEIR APPLICATIONS, AND COMPOSITIONS AND METHODS FOR PRODUCING THEM CRY1, COL1A1, COL14A1 LMNA 966/4885NPC1 2625/4885CYP1A2 3059/4885
US-20090068379-A1 DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE OCIAD1, OCIAD2, DAXX LMNA 3096/4885NPC1 2485/4885CYP1A2 3242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.