SCHEMBL9607893

SCHEMBL9607893

C=CC(=O)Oc1ccc(-c2ccc(OC(=O)C=C)c(F)c2F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.36
AR P10275 1/20 0.34
PRKCZ Q05513 1/20 0.34
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
PTGS2 P35354 6/20 0.33
XDH P47989 1/20 0.32
PTGS1 P23219 3/20 0.32
THRB P10828 2/20 0.32
ALOX5 P09917 2/20 0.32
THRA P10827 1/20 0.32
ERN1 O75460 1/20 0.32
EGFR P00533 1/20 0.32
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646524 0.94 ALOX5 (0.41) TYMSARPRKCZTSHRPTGS2
SCHEMBL19882317 0.92 AR (0.44) ARPRKCZMAPK1PTGS2XDH
SCHEMBL21417666 0.92 AR (0.41) ARPRKCZMAPK1PTGS2XDH
SCHEMBL22600373 0.91 ALOX5 (0.33) TYMSARPRKCZPTGS2XDH
SCHEMBL22600374 0.91 ALOX5 (0.33) TYMSARPRKCZPTGS2XDH
SCHEMBL18438987 0.91 TYMS (0.33) TYMSARPRKCZXDHERN1
SCHEMBL17309263 0.91 KDM4E (0.39) TYMSESR1ESR2
SCHEMBL20343012 0.90 PRKCZ (0.36) ARPRKCZPTGS2PTGS1THRB
SCHEMBL2604626 0.89 TYMS (0.42) TYMSARPOLBTSHRMAPK1
SCHEMBL18869353 0.89 TSHR (0.42) PRKCZPOLBTSHRMAPK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-2557140-A2 Liquid-crystalline medium Merck Patent GmbH (DE) 2013-02-13 EP disclosed
WO-2012130380-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-10-04 WO disclosed
WO-2012126562-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-09-27 WO disclosed
WO-2012097858-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-07-26 WO disclosed
WO-2012079710-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-21 WO disclosed
WO-2012072201-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-07 WO disclosed
WO-2012069151-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-05-31 WO disclosed
EP-2457975-A2 Liquid-crystalline mixtures Merck Patent GmbH (DE) 2012-05-30 EP disclosed
US-20100033662-A1 LIQUID CRYSTAL DISPLAY SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-11 US disclosed
US-20100033662-A1 LIQUID CRYSTAL DISPLAY SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-11 US disclosed