SCHEMBL9607913

SCHEMBL9607913

CN1CCN(c2ccccc2)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
BRD4 O60885 2/20 0.44
BRD2 P25440 1/20 0.44
BRD3 Q15059 1/20 0.44
TP53 P04637 2/20 0.41
HTR1A P08908 1/20 0.40
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
TMEM97 Q5BJF2 1/20 0.40
P2RY1 P47900 1/20 0.37
CNR2 P34972 1/20 0.37
ADRA2C P18825 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433139 0.88 TP53 (0.43) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL25896631 0.86 MAPT (0.44) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL26495670 0.85 TP53 (0.41) RAB9AKMT2ABRD4TP53HTR1A
SCHEMBL25889913 0.85 TP53 (0.41) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL8276420 0.82 CNR2 (0.46) MEN1KMT2ATP53CNR2ADRA2C
SCHEMBL29941513 0.82 CNR2 (0.46) MEN1KMT2ATP53CNR2ADRA2C
SCHEMBL30685549 0.81 MAPT (0.42) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL12153469 0.81 MAPT (0.42) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL26495382 0.81 ALDH1A1 (0.41) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL29843853 0.79 MAPT (0.41) SIGMAR1MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 WO disclosed
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
US-8536173-B2 Tetrahydroquinoxaline urea derivatives as modulators of 11-B-hydroxysteroid dehydrogenase type I SANOFI (FR) 2013-09-17 US disclosed
US-8530473-B2 Tetrahydroquinoxaline urea derivatives as modulators of 11β-hydroxysteroid dehydrogenase type 1 SANOFI (FR) 2013-09-10 US disclosed
US-8530657-B2 Substituted adamantanes and their therapeutic application SANOFI (FR) 2013-09-10 US disclosed
US-20100119964-A1 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. 2010-05-13 US disclosed
US-20100119964-A1 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. 2010-05-13 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-7220522-B2 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2007-05-22 US disclosed
US-7220522-B2 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2007-05-22 US disclosed