Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516686 | 0.90 | LPAR1 (0.33) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL9608237 | 0.88 | LPAR1 (0.32) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL12960587 | 0.88 | LPAR1 (0.32) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL12960581 | 0.84 | CNR1 (0.34) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL9608233 | 0.83 | LPAR1 (0.33) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL9608204 | 0.82 | LPAR2 (0.48) | LPAR1LPAR2CNR1CNR2 | |
| SCHEMBL9608234 | 0.82 | LPAR1 (0.32) | LPAR1LPAR2CNR1CNR2KDM4E | |
| SCHEMBL9608207 | 0.82 | LPAR2 (0.42) | LPAR1LPAR2CNR1CNR2 | |
| SCHEMBL9608153 | 0.82 | GALR3 (0.41) | LPAR1LPAR2CNR1CNR2 | |
| SCHEMBL9608203 | 0.81 | LPAR2 (0.45) | LPAR1LPAR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-8586505-B2 | 4-(3-butynyl)aminopyrimidine derivatives as pest control agents for agricultural and horticultural use | SDS BIOTECH K. K. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | HCN1, HCN2, HCN3 | LPAR1 4476/4885LPAR2 4487/4885CNR1 2359/4885 |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | LPAR1 2268/4885LPAR2 1454/4885CNR1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.