SCHEMBL9608415

SCHEMBL9608415

COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3ccc(NC(C)=O)cc3O)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.56
MEN1 O00255 10/20 0.56
KMT2A Q03164 10/20 0.56
NPSR1 Q6W5P4 3/20 0.56
POLB P06746 1/20 0.56
ALDH1A1 P00352 7/20 0.49
HPGD P15428 5/20 0.49
KDM4E B2RXH2 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
RXFP1 Q9HBX9 2/20 0.49
EGFR P00533 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4A O75164 1/20 0.47
GAA P10253 2/20 0.47
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 1/20 0.46
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
CASP3 P42574 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609299 0.88 MAPT (0.55) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608434 0.87 MAPT (0.58) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL15910001 0.87 MAPT (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608388 0.87 MAPT (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608447 0.85 MAPT (0.55) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL13962486 0.85 KMT2A (0.61) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL12755014 0.85 MAPT (0.51) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608456 0.85 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608416 0.84 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9609243 0.84 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885MEN1 2282/4885KMT2A 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.