SCHEMBL9608417

SCHEMBL9608417

COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3ccc(C(C)(C)C)cc3O)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MAPT P10636 5/20 0.52
NPSR1 Q6W5P4 2/20 0.52
POLB P06746 2/20 0.52
EGFR P00533 2/20 0.51
KDM4A O75164 1/20 0.48
HPGD P15428 4/20 0.45
ALDH1A1 P00352 4/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 2/20 0.42
ADORA3 P0DMS8 1/20 0.42
TSHR P16473 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA2B P29275 1/20 0.42
ADORA1 P30542 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 2/20 0.42
PDE5A O76074 1/20 0.41
ABCC1 P33527 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608437 0.90 MAPT (0.51) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608535 0.89 MEN1 (0.51) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608434 0.88 MAPT (0.58) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608388 0.88 MAPT (0.60) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL15910001 0.88 MAPT (0.60) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL12228440 0.85 EGFR (0.59) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL12755019 0.85 EGFR (0.49) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9609299 0.84 MAPT (0.55) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608420 0.84 MAPT (0.58) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL15908071 0.84 MAPT (0.57) MEN1KMT2AMAPTNPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.