SCHEMBL9608461

SCHEMBL9608461

COC(=O)c1ccc(-c2nc(-c3ccc(C)cc3O)nc(-c3ccc4ccccc4c3O)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.48
TP53 P04637 2/20 0.48
EGFR P00533 1/20 0.47
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 2/20 0.45
HPGD P15428 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
ATM Q13315 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
POLB P06746 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608463 0.90 MAPT (0.49) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL12228473 0.89 EGFR (0.53) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL9609270 0.88 EGFR (0.46) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL12755064 0.88 EGFR (0.50) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL12228445 0.87 EGFR (0.61) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL12755042 0.87 MAPT (0.55) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL17917575 0.86 EGFR (0.47) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL9608420 0.86 MAPT (0.58) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL12755016 0.86 TDP1 (0.56) MAPTTP53EGFRKDM4EALDH1A1
SCHEMBL9608464 0.85 HTT (0.47) MAPTTP53EGFRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885TP53 3490/4885EGFR 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.