SCHEMBL9608464

SCHEMBL9608464

COC(=O)c1ccc(-c2nc(-c3ccc(C)cc3O)nc(-c3ccc4ncccc4c3O)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
ALOX15 P16050 1/20 0.47
MAPT P10636 6/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
ATM Q13315 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TP53 P04637 1/20 0.45
EGFR P00533 1/20 0.41
SLC2A1 P11166 1/20 0.41
KMT2A Q03164 3/20 0.40
MITF O75030 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609300 0.89 ALOX15 (0.46) HTTALOX15NPC1RAB9AEGFR
SCHEMBL12755066 0.88 ALOX15 (0.58) HTTALOX15MAPTKDM4EALDH1A1
SCHEMBL17917588 0.87 HTT (0.45) HTTALOX15MAPTKDM4EALDH1A1
SCHEMBL9608461 0.85 MAPT (0.48) MAPTKDM4EALDH1A1HPGDNPC1
SCHEMBL12755042 0.84 MAPT (0.55) MAPTKDM4EALDH1A1HPGDNPC1
SCHEMBL12755016 0.82 TDP1 (0.56) MAPTKDM4EALDH1A1HPGDNPC1
SCHEMBL12228445 0.81 EGFR (0.61) MAPTKDM4EALDH1A1HPGDNPC1
SCHEMBL9608547 0.81 ALOX15 (0.46) HTTALOX15MAPTKDM4EALDH1A1
SCHEMBL9608420 0.81 MAPT (0.58) ALOX15MAPTKDM4EALDH1A1HPGD
SCHEMBL12755017 0.79 MAPT (0.51) MAPTKDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 HTT 1355/4885ALOX15 2823/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.