SCHEMBL9608474

SCHEMBL9608474

CCCCCCOC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3ccc(C)cc3O)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
CNR2 P34972 2/20 0.49
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CNR1 P21554 1/20 0.47
ESR1 P03372 3/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
STS P08842 5/20 0.44
LMNA P02545 3/20 0.43
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608472 0.96 MAPT (0.48) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL12755002 0.95 CNR2 (0.56) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL9608402 0.93 ALDH1A1 (0.56) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL12755000 0.91 CNR2 (0.52) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL9608473 0.88 MEN1 (0.58) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9608406 0.88 ESR1 (0.56) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL9609332 0.88 MAPT (0.48) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL9608480 0.88 PRSS1 (0.44) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL9608477 0.88 PRSS1 (0.44) MAPTCNR2ALDH1A1NPC1RAB9A
SCHEMBL31195650 0.85 CNR2 (0.62) MAPTCNR2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885CNR2 2878/4885ALDH1A1 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.