SCHEMBL9608475

SCHEMBL9608475

CCCCC(CC)COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3ccc(C)cc3O)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.53
ALDH1A1 P00352 6/20 0.49
CYP3A4 P08684 3/20 0.49
HSD17B10 Q99714 2/20 0.49
MAPK1 P28482 2/20 0.49
TSHR P16473 2/20 0.49
CA2 P00918 1/20 0.48
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
KMT2A Q03164 5/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 4/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ATM Q13315 2/20 0.36
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12755003 0.95 LMNA (0.51) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608403 0.93 LMNA (0.60) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608480 0.93 PRSS1 (0.44) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608477 0.93 PRSS1 (0.44) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9609298 0.89 LMNA (0.51) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL12755004 0.88 PRSS1 (0.45) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL12755011 0.88 PRSS1 (0.45) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608478 0.88 MAPT (0.41) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608476 0.86 MAPT (0.41) LMNAALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL9608418 0.85 PRSS1 (0.50) LMNAALDH1A1CYP3A4HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 LMNA 1414/4885ALDH1A1 847/4885CYP3A4 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.