SCHEMBL9608484

SCHEMBL9608484

Oc1ccccc1-c1nc(-c2cccc(C(F)(F)F)c2)nc(-c2ccccc2O)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.55
LMNA P02545 1/20 0.55
ADORA2A P29274 4/20 0.53
ADORA1 P30542 3/20 0.53
TSHR P16473 2/20 0.53
ALOX15 P16050 2/20 0.53
ADORA3 P0DMS8 1/20 0.53
ADORA2B P29275 1/20 0.53
PTPN5 P54829 1/20 0.51
CHUK O15111 1/20 0.48
TXNRD1 Q16881 1/20 0.48
NOX4 Q9NPH5 1/20 0.48
CNR2 P34972 1/20 0.48
MAPK1 P28482 1/20 0.44
MAOB P27338 1/20 0.44
RORC P51449 1/20 0.44
RORB Q92753 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608549 0.91 LMNA (0.47) POLBLMNAADORA2AADORA1TSHR
SCHEMBL9609224 0.88 NR1H4 (0.52) POLBLMNAADORA2AADORA1TSHR
SCHEMBL9609271 0.88 POLB (0.54) POLBLMNAADORA2AADORA1TSHR
SCHEMBL2048141 0.84 PTPN5 (0.69) POLBLMNAADORA2AADORA1ALOX15
SCHEMBL30689246 0.84 PTPN5 (0.69) POLBLMNAADORA2AADORA1ALOX15
SCHEMBL12754991 0.84 CYP1A2 (0.47) POLBLMNAADORA2AADORA1TSHR
SCHEMBL9608441 0.84 CHUK (0.60) POLBLMNAADORA2AADORA1TSHR
SCHEMBL15910009 0.83 CHUK (0.53) POLBLMNAADORA2AADORA1TSHR
SCHEMBL9608390 0.83 CHUK (0.67) POLBLMNAADORA2AADORA1TSHR
SCHEMBL20426104 0.82 ABCG2 (0.55) ADORA2AADORA1TSHRALOX15CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460799-B1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORP (JP) 2018-05-02 EP disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
EP-2301995-A1 Polycarbonate resin composition containing triazine compound and molded article using the same Fujifilm Corporation (JP) 2011-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 POLB 246/4885LMNA 1414/4885ADORA2A 1612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.