SCHEMBL9608527

SCHEMBL9608527

CCCCCCOc1ccc(-c2nc(-c3cccc(C(=O)OC)c3)nc(-c3ccccc3O)n2)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.53
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
SMPD1 P17405 3/20 0.45
NR1H4 Q96RI1 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
PLA2G4B P0C869 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608414 0.90 PTPN11 (0.48) PTPN11MEN1MAPTKMT2ANPSR1
SCHEMBL12228454 0.87 PTPN11 (0.52) PTPN11MAPTRAB9A
SCHEMBL9608500 0.85 CNR2 (0.56) ALDH1A1MAPTNPC1RAB9A
SCHEMBL9608530 0.85 MEN1 (0.53) MEN1ALDH1A1GAAMAPTHPGD
SCHEMBL9608487 0.83 MEN1 (0.60) MEN1ALDH1A1GAAMAPTHPGD
SCHEMBL23285271 0.83 PTPN11 (0.46) PTPN11MEN1ALDH1A1MAPTKMT2A
SCHEMBL9608499 0.82 CNR2 (0.52) MEN1MAPTHPGDKMT2ANPC1
SCHEMBL38951 0.82 PTPN11 (0.54) PTPN11GAAPLA2G4B
SCHEMBL1468260 0.82 PTPN11 (0.54) PTPN11GAAPLA2G4B
SCHEMBL1467411 0.82 PTPN11 (0.54) PTPN11GAAPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 PTPN11 4364/4885MEN1 2282/4885ALDH1A1 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.