SCHEMBL9608414

SCHEMBL9608414

CCCCCCOc1ccc(-c2nc(-c3ccc(C(=O)OC)cc3)nc(-c3ccccc3O)n2)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.48
MAPT P10636 3/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RARB P10826 3/20 0.45
PLA2G2A P14555 1/20 0.45
RAB9A P51151 1/20 0.44
EGFR P00533 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
KDM4A O75164 1/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
PLK1 P53350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228454 0.95 PTPN11 (0.52) PTPN11MAPTRARBPLA2G2ARAB9A
SCHEMBL9608527 0.90 PTPN11 (0.53) PTPN11MAPTMEN1KMT2ANPSR1
SCHEMBL12228409 0.90 PLA2G2A (0.50) PTPN11MAPTRARBPLA2G2A
SCHEMBL23285271 0.89 PTPN11 (0.46) PTPN11MAPTMEN1KMT2ANPSR1
SCHEMBL12754391 0.89 MAPT (0.50) MAPTMEN1POLBKMT2ANPSR1
SCHEMBL9609332 0.87 MAPT (0.48) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL12755012 0.87 RARB (0.48) PTPN11MAPTKMT2ARARBPLK1
SCHEMBL1630438 0.84 PTPN11 (0.52) PTPN11RARB
SCHEMBL10090891 0.84 PTPN11 (0.52) PTPN11RARB
SCHEMBL5550301 0.84 PTPN11 (0.52) PTPN11RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 PTPN11 4364/4885MAPT 1774/4885MEN1 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.