SCHEMBL9608536

SCHEMBL9608536

COC(=O)c1cccc(-c2nc(-c3ccccc3O)nc(-c3cc(OC)ccc3O)n2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MAPT P10636 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
HPGD P15428 1/20 0.52
NPC1 O15118 2/20 0.48
RAB9A P51151 1/20 0.48
PLAU P00749 2/20 0.47
PLAT P00750 2/20 0.47
PLG P00747 1/20 0.47
ADORA2A P29274 2/20 0.47
ERN1 O75460 2/20 0.46
POLB P06746 1/20 0.46
NEK1 Q96PY6 1/20 0.45
RXFP1 Q9HBX9 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
ADORA2B P29275 1/20 0.44
ADORA1 P30542 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608530 0.94 MEN1 (0.53) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608487 0.91 MEN1 (0.60) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608545 0.90 MEN1 (0.55) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL12228399 0.88 PLAU (0.49) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608419 0.88 MEN1 (0.53) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608537 0.87 MEN1 (0.57) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608540 0.86 MEN1 (0.52) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9608543 0.86 MEN1 (0.56) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL12228442 0.85 PLAU (0.54) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL12228457 0.85 EGFR (0.55) MEN1KMT2AMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.