SCHEMBL9608419

SCHEMBL9608419

COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3cc(OC)ccc3O)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
MAPT P10636 4/20 0.53
NPSR1 Q6W5P4 2/20 0.53
POLB P06746 1/20 0.53
NPC1 O15118 1/20 0.50
KDM4A O75164 1/20 0.49
EGFR P00533 1/20 0.48
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
HPGD P15428 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 2/20 0.46
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
RXFP1 Q9HBX9 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTPRC P08575 1/20 0.43
PTPRF P10586 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609244 0.94 MEN1 (0.54) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL12228457 0.94 EGFR (0.55) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608454 0.90 MAPT (0.57) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608448 0.90 MAPT (0.50) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608462 0.89 MAPT (0.56) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608388 0.89 MAPT (0.60) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL15910001 0.89 MAPT (0.60) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL9608536 0.88 MEN1 (0.52) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL12228365 0.88 EGFR (0.60) MEN1KMT2AMAPTNPSR1POLB
SCHEMBL15908071 0.88 MAPT (0.57) MEN1KMT2AMAPTNPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460799-B1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORP (JP) 2018-05-02 EP disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.