Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682746 | 0.95 | MAPT (0.53) | MAPTHCAR2AKR1B10AKR1B1TRPV1 | |
| SCHEMBL9608866 | 0.92 | MAPT (0.51) | MAPTHCAR2AKR1B10AKR1B1GPR52 | |
| SCHEMBL10453292 | 0.84 | MAPT (0.45) | MAPTHCAR2AKR1B10AKR1B1GPR52 | |
| SCHEMBL10593990 | 0.82 | MAPT (0.52) | MAPTHCAR2LMNAMDM4MDM2 | |
| SCHEMBL10593997 | 0.82 | MAPT (0.52) | MAPTHCAR2LMNAMDM4MDM2 | |
| SCHEMBL10896168 | 0.82 | ALOX5 (0.48) | MAPTALOX5 | |
| SCHEMBL10896173 | 0.82 | ALOX5 (0.48) | MAPTALOX5 | |
| SCHEMBL1268422 | 0.81 | MAPT (0.62) | MAPTHCAR2GPR52 | |
| SCHEMBL1268421 | 0.81 | MAPT (0.62) | MAPTHCAR2GPR52 | |
| SCHEMBL8515991 | 0.81 | TAAR1 (0.51) | MAPTHCAR2GPR52TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |