Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591778 | 0.85 | MAPT (0.47) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL15932097 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL22609332 | 0.78 | CYP1A2 (0.50) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL159255 | 0.77 | CYP1A2 (0.49) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL17288520 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL6372052 | 0.73 | MRGPRX4 (0.45) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL22890098 | 0.72 | CYP1A2 (0.44) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7697875 | 0.71 | MPO (0.47) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL21607841 | 0.70 | HCAR2 (0.66) | KMT2ACYP1A2MAPK1TP53POLB | |
| SCHEMBL6317015 | 0.70 | CYP1A2 (0.41) | MAPTALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |