Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178395 | 0.81 | KDM1A (0.51) | MAPTKDM4EMEN1KMT2AKDM1A | |
| SCHEMBL30471820 | 0.81 | KDM1A (0.51) | MAPTKDM4EMEN1KMT2AKDM1A | |
| SCHEMBL12649387 | 0.79 | CASP3 (0.44) | MAPTKDM4EMEN1KMT2AKDM1A | |
| SCHEMBL16797049 | 0.78 | MEN1 (0.45) | BCDIN3DMAPTKDM4EMEN1KMT2A | |
| SCHEMBL5871935 | 0.78 | KDM1A (0.41) | BCDIN3DMAPTKDM4EMEN1KMT2A | |
| SCHEMBL3229511 | 0.78 | NNMT (0.44) | MAPTKDM4EMEN1KMT2AKDM1A | |
| SCHEMBL27639119 | 0.78 | KDM1A (0.41) | BCDIN3DMAPTKDM4EMEN1KMT2A | |
| SCHEMBL31666977 | 0.78 | TAAR1 (0.52) | ATMTAAR1BCDIN3DKDM4EMEN1 | |
| SCHEMBL1967473 | 0.78 | TAAR1 (0.52) | ATMTAAR1BCDIN3DKDM4EMEN1 | |
| SCHEMBL23252933 | 0.77 | TAAR1 (0.56) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |