SCHEMBL960889

SCHEMBL960889

CCCOC(=O)C1=CCC(C)(C(=O)OCCC)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
LMNA P02545 1/20 0.39
TSHR P16473 3/20 0.38
ESR1 P03372 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
KDR P35968 1/20 0.38
KDM4E B2RXH2 3/20 0.33
BRD4 O60885 1/20 0.33
POLB P06746 1/20 0.33
STS P08842 1/20 0.33
HPGD P15428 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963678 0.91 TSHR (0.43) ALDH1A1LMNATSHRESR1TDP1
SCHEMBL962304 0.84 BRD4 (0.43) ALDH1A1LMNATSHRESR1KDM4E
SCHEMBL959296 0.72 CHRM3 (0.39) LMNATSHRCHRM1KDM4EPOLB
SCHEMBL7197439 0.70 ALDH1A1 (0.50) ALDH1A1LMNATSHRESR1TDP1
SCHEMBL817939 0.69 ALDH1A1 (0.46) ALDH1A1LMNATSHRESR1TDP1
SCHEMBL1439148 0.68 ALDH1A1 (0.38) ALDH1A1LMNATSHRTDP1CHRM1
SCHEMBL3009190 0.66 HCAR2 (0.34) ALDH1A1LMNATSHRESR1TDP1
SCHEMBL1439277 0.66 CYP3A4 (0.40) ALDH1A1LMNATSHRTDP1CHRM1
SCHEMBL9858356 0.66 ALDH1A1 (0.46) ALDH1A1LMNATSHRESR1TDP1
SCHEMBL18819444 0.66 ALDH1A1 (0.38) ALDH1A1LMNATSHRESR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617424-B1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME KONICA MINOLTA OPTO INC (JP) 2012-08-15 EP disclosed
US-20110111256-A1 Optical Element, Method for Producing Optical Element, and Method for Manufacturing Electronic Device KONICA MINOLTA OPTO, INC. (JP) 2011-05-12 US disclosed
US-20110006447-A1 Method for Producing Hybrid Optical Element Grouping KONICA MINOLTA OPTO, INC. (JP) 2011-01-13 US disclosed
EP-2202739-A1 Diffraction optical device and optical pickup device using the same Konica Minolta Opto, Inc. (JP) 2010-06-30 EP disclosed
US-20080310284-A1 DIFFRACTIVE OPTICAL ELEMENT AND OPTICAL PICKUP APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-12-18 US disclosed
EP-1617424-A1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME Konica Minolta Opto, Inc. (JP) 2006-01-18 EP disclosed