SCHEMBL9608963

SCHEMBL9608963

CCc1ccc(C(=CC=C(c2cccc(N(CC)CC)c2)c2cccc(N(CC)CC)c2)c2ccc(CC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 5/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 3/20 0.35
MEN1 O00255 2/20 0.35
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
MCL1 Q07820 1/20 0.35
NOX1 Q9Y5S8 1/20 0.35
LMNA P02545 4/20 0.35
HTT P42858 2/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
GFER P55789 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12316357 0.90 ALDH1A1 (0.45) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL279128 0.90 ALDH1A1 (0.45) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL13498625 0.88 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL759763 0.88 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL14283593 0.88 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL328020 0.87 ALDH1A1 (0.43) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL279462 0.85 ALDH1A1 (0.41) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL14256373 0.82 TSHR (0.53) ALDH1A1CYP3A4MAPTKMT2AMAPK1
SCHEMBL14283587 0.79 NR1H2 (0.49) ALDH1A1CYP3A4KMT2ATSHRL3MBTL1
SCHEMBL9607501 0.78 ALDH1A1 (0.37) ALDH1A1CYP3A4MAPTKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed