SCHEMBL279128

SCHEMBL279128

CCN(CC)c1cccc(C(=CC=C(c2ccc(CO)cc2)c2ccc(CO)cc2)c2cccc(N(CC)CC)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 1/20 0.45
S1PR1 P21453 7/20 0.41
MAPT P10636 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 2/20 0.35
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
MCL1 Q07820 1/20 0.35
NOX1 Q9Y5S8 1/20 0.35
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608963 0.90 ALDH1A1 (0.46) ALDH1A1CYP3A4S1PR1MAPTMEN1
SCHEMBL12316357 0.89 ALDH1A1 (0.45) ALDH1A1CYP3A4S1PR1MAPTMEN1
SCHEMBL13498625 0.86 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL14283593 0.86 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL759763 0.86 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL328020 0.86 ALDH1A1 (0.43) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL279462 0.84 ALDH1A1 (0.41) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL14256373 0.81 TSHR (0.53) ALDH1A1CYP3A4S1PR1MAPTKMT2A
SCHEMBL14283587 0.78 NR1H2 (0.49) ALDH1A1CYP3A4KMT2ATSHR
SCHEMBL9607501 0.76 ALDH1A1 (0.37) ALDH1A1CYP3A4MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070100164-A1 Arylamine processes XEROX CORPORATION (US) 2007-05-03 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070100164-A1 Arylamine processes AHR, INMT, TYR ALDH1A1 715/4885CYP3A4 33/4885S1PR1 4517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.