Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104161 | 0.97 | XIAP (0.36) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL14140109 | 0.95 | CYP3A4 (0.36) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL10331862 | 0.87 | ACE (0.40) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL12034318 | 0.87 | ACE (0.40) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL9609014 | 0.87 | ACE (0.40) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL26256186 | 0.87 | ACE (0.40) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL13259956 | 0.85 | F2 (0.38) | F2PLGXIAPCYP3A4TSHR | |
| SCHEMBL8358700 | 0.83 | XIAP (0.38) | XIAPCYP3A4TSHRTDP1MAPT | |
| SCHEMBL5832039 | 0.83 | XIAP (0.38) | XIAPCYP3A4TSHRTDP1MAPT | |
| SCHEMBL5832021 | 0.83 | XIAP (0.38) | XIAPCYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |