SCHEMBL9609269

SCHEMBL9609269

CC1=CC(C)(C)Nc2ccc3c(O)cccc3c21

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 16/20 0.55
▸ NR3C1 P04150 5/20 0.46
▸ AR P10275 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ NR3C2 P08235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397969 0.76 PGR (0.57) PGRNR3C1AR
Hydrochloric Acid SCHEMBL6723833 0.73 PGR (0.54) PGRNR3C1ARALDH1A1KDM4E
SCHEMBL11653695 0.72 ALDH1A1 (0.56) PGRNR3C1ARALDH1A1HSD17B10
SCHEMBL2392689 0.70 PGR (0.50) PGRNR3C1ARALDH1A1HSD17B10
SCHEMBL12886106 0.69 PGR (0.74) PGRNR3C1ARALDH1A1HSD17B10
SCHEMBL12236606 0.67 PGR (0.44) PGRNR3C1ARALDH1A1HSD17B10
SCHEMBL6720477 0.66 PGR (0.49) PGRNR3C1ARHSD17B10KDM4E
SCHEMBL2393047 0.66 PGR (0.73) PGRNR3C1ARALDH1A1HSD17B10
SCHEMBL5035638 0.66 PGR (0.57) PGRNR3C1ARNR3C2
SCHEMBL2395158 0.65 PGR (0.45) PGRNR3C1ARALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023004400-A1 DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION Life Technologies Corporation (US) 2023-01-26 — — WO disclosed
US-9551029-B2 Methods and kits using extended rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2017-01-24 — — US disclosed
US-20160122813-A1 Methods And Kits Using Extended Rhodamine Dyes THE PERKIN-ELMER CORPORATION 2016-05-05 — — US disclosed
US-9309561-B2 Methods and kits using extended rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2016-04-12 — — US disclosed
US-20140171336-A1 Methods and Kits Using Extended Rhodamine Dyes Life Technologies Corporation (US) 2014-06-19 — — US disclosed
US-8628975-B2 Methods and kits using extended rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2014-01-14 — — US disclosed
US-20120135885-A1 Methods and Kits Using Extended Rhodamine Dyes Life Technologies Corporation (US) 2012-05-31 — — US disclosed
US-8124746-B2 Methods and kits using extended rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2012-02-28 — — US disclosed
US-20110053282-A1 Methods and Kits Using Extended Rhodamine Dyes Life Technologies Corporation (US) 2011-03-03 — — US disclosed
US-7776568-B2 Rhodamine dye compounds for patterns with DNA sequences for kits APPLIED BIOSYSTEMS, LLC (US) 2010-08-17 — — US disclosed
US-7776568-B2 Rhodamine dye compounds for patterns with DNA sequences for kits APPLIED BIOSYSTEMS, LLC (US) 2010-08-17 — — US disclosed
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