SCHEMBL9609313

SCHEMBL9609313

COC(=O)c1ccc(C(=O)NC(=O)c2cc(Cl)ccc2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
P2RX1 P51575 6/20 0.52
KCNMA1 Q12791 2/20 0.50
KDM1A O60341 1/20 0.50
LMNA P02545 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TMPRSS4 Q9NRS4 5/20 0.49
P2RX4 Q99571 3/20 0.49
P2RX7 Q99572 3/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA12 O43570 1/20 0.49
CA7 P43166 1/20 0.49
XDH P47989 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10272284 0.84 MEN1 (0.74) MEN1KMT2AP2RX1KCNMA1KDM4E
SCHEMBL11295587 0.84 KDM4E (0.62) MEN1KMT2AP2RX1KCNMA1LMNA
SCHEMBL9609319 0.83 CA1 (0.56) MEN1KMT2AP2RX1LMNAKDM4E
SCHEMBL4020108 0.80 PTGER4 (0.53) MEN1KMT2AP2RX1LMNAKDM4E
SCHEMBL18341280 0.80 TMPRSS4 (0.71) MEN1KMT2AP2RX1KCNMA1LMNA
SCHEMBL123068 0.80 CA1 (0.67) MEN1KMT2AP2RX1KCNMA1LMNA
SCHEMBL9609242 0.79 NPC1 (0.63) MEN1KMT2AKDM1ALMNAKDM4E
SCHEMBL16148001 0.79 KCNMA1 (0.59) MEN1KMT2AP2RX1KCNMA1LMNA
SCHEMBL19064514 0.78 P2RX1 (0.62) MEN1KMT2AP2RX1KCNMA1LMNA
SCHEMBL9609273 0.77 MEN1 (0.58) MEN1KMT2AKDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
EP-2460799-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM Corporation (JP) 2012-06-06 EP disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-20110077330-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885P2RX1 1040/4885
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION AVPR1B, H1-0, H1-2 MEN1 1396/4885KMT2A 1754/4885P2RX1 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.