SCHEMBL9609318

SCHEMBL9609318

COc1ccc(-c2nc(-c3ccc(C(=O)OCC(CCC(C)CC(C)(C)C)C(C)CC(C)(C)C)cc3)nc(-c3ccccc3O)n2)c(O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.37
MAPT P10636 5/20 0.37
KMT2A Q03164 5/20 0.37
HSD17B10 Q99714 3/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
HSP90AA1 P07900 1/20 0.37
XBP1 P17861 1/20 0.37
ALOX12 P18054 1/20 0.37
ALOX15 P16050 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
NPC1 O15118 1/20 0.35
THRB P10828 1/20 0.35
POLB P06746 1/20 0.34
ADRB2 P07550 3/20 0.34
ADRB1 P08588 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228405 0.96 MEN1 (0.37) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL9608412 0.93 MAPT (0.39) MEN1MAPTKMT2AHSD17B10SMN1; SMN2
SCHEMBL9608479 0.91 KMT2A (0.39) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL12755009 0.86 NPC1 (0.35) MEN1MAPTKMT2AHSD17B10SMN1; SMN2
SCHEMBL9609314 0.86 MAPT (0.36) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL17917580 0.85 ADORA2A (0.40) MEN1MAPTKMT2AHSD17B10SMN1; SMN2
SCHEMBL12228406 0.82 MEN1 (0.37) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL9608482 0.81 MAPT (0.41) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL9609333 0.79 MAPT (0.55) MEN1MAPTKMT2AHSD17B10LMNA
SCHEMBL9609304 0.79 MEN1 (0.38) MEN1MAPTKMT2AHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
EP-2460799-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM Corporation (JP) 2012-06-06 EP disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885MAPT 1774/4885KMT2A 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.