SCHEMBL9609304

SCHEMBL9609304

COc1ccc(-c2nc(-c3ccc(C(=O)OCC(CCCCC(C)C)CCC(C)C)cc3)nc(-c3ccccc3O)n2)c(O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.38
KMT2A Q03164 6/20 0.38
MAPT P10636 5/20 0.38
HSD17B10 Q99714 3/20 0.38
ALOX15 P16050 3/20 0.38
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.36
LMNA P02545 6/20 0.36
NPSR1 Q6W5P4 2/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
HSP90AA1 P07900 1/20 0.36
XBP1 P17861 1/20 0.36
ALOX12 P18054 1/20 0.36
THRB P10828 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228401 0.96 THRB (0.38) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9608408 0.92 MAPT (0.41) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9609301 0.90 PRSS1 (0.43) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9609317 0.90 PRSS1 (0.43) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9608476 0.89 MAPT (0.41) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9609339 0.89 MAPT (0.38) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL9609298 0.87 LMNA (0.51) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL12228402 0.86 PRSS1 (0.43) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL12228407 0.86 PRSS1 (0.43) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL12829542 0.85 LMNA (0.37) MEN1KMT2AMAPTHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.