SCHEMBL9609702

SCHEMBL9609702

CCO[Si](CCCSCc1ccc2c(ccc3c4ccccc4ccc23)c1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
AKR1B1 P15121 1/20 0.33
CYP1A2 P05177 5/20 0.32
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP1B1 Q16678 2/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2D6 P10635 3/20 0.32
CYP2C19 P33261 3/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2E1 P05181 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2B6 P20813 1/20 0.32
PDE7A Q13946 1/20 0.32
HPGD P15428 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609734 0.93 CYP1A2 (0.36) SMN1; SMN2LMNACYP1A2CYP2A6ALDH1A1
SCHEMBL9609727 0.89 CYP1A2 (0.42) SMN1; SMN2LMNACYP1A2CYP2A6CYP2D6
SCHEMBL9609701 0.81 MC5R (0.45) MAPK1
SCHEMBL9609693 0.81 TLR8 (0.39) SMN1; SMN2LMNACYP1A2ALDH1A1CYP2D6
SCHEMBL9609742 0.80 KDM4E (0.35) KDM4E
SCHEMBL6073782 0.78 CYP2C19 (0.44) SMN1; SMN2LMNACYP1A2ALDH1A1HSD17B10
SCHEMBL13029170 0.75 LMNA (0.33) SMN1; SMN2LMNACYP1A2ALDH1A1CYP2D6
SCHEMBL9609715 0.74 MAPT (0.47) SMN1; SMN2LMNAALDH1A1MAPTKMT2A
SCHEMBL9609732 0.73 MC5R (0.44) KMT2AMAPK1
SCHEMBL9609747 0.73 MAPT (0.34) SMN1; SMN2CYP1A2ALDH1A1HSD17B10CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L HPRT1 3749/4885SMN1; SMN2 992/4885LMNA 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.