SCHEMBL9609715

SCHEMBL9609715

CCO[Si](CCCSCc1ccc2c(c1)C(=O)c1ccccc1-2)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PTPRC P08575 1/20 0.37
SOAT1 P35610 8/20 0.35
S100A4 P26447 2/20 0.35
HSP90AB1 P08238 1/20 0.35
CASP3 P42574 1/20 0.35
ATM Q13315 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
GABRP O00591 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609710 0.81 MAPT (0.47) MAPTNPC1LMNAMAPK1RAB9A
SCHEMBL9609727 0.79 CYP1A2 (0.42) MAPTNPC1LMNARAB9ASMN1; SMN2
SCHEMBL6073782 0.78 CYP2C19 (0.44) MAPTNPC1LMNARAB9ASMN1; SMN2
SCHEMBL12187315 0.77 NPC1 (0.49) MAPTNPC1LMNAMAPK1RAB9A
SCHEMBL9609734 0.76 CYP1A2 (0.36) MAPTNPC1LMNAMAPK1RAB9A
SCHEMBL13029170 0.75 LMNA (0.33) MAPTNPC1LMNARAB9ASMN1; SMN2
SCHEMBL9609702 0.74 HPRT1 (0.33) MAPTNPC1LMNAMAPK1RAB9A
SCHEMBL9609693 0.74 TLR8 (0.39) MAPTLMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL9609747 0.73 MAPT (0.34) MAPTMAPK1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1762046 0.72 NPC1 (0.53) MAPTNPC1LMNAMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L MAPT 284/4885NPC1 1763/4885LMNA 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.