SCHEMBL9609711

SCHEMBL9609711

CCO[Si](CCC(O)COCc1ccc2c(c1)Cc1ccccc1-2)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP17A1 P05093 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
HTT P42858 1/20 0.36
PDE10A Q9Y233 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609708 0.82 DRD2 (0.42) MMP12MMP13TSHRALDH1A1ATM
SCHEMBL9609730 0.80 CASR (0.47) ALDH1A1
SCHEMBL9609736 0.77 CASR (0.38) ALDH1A1PRMT5WDR77
SCHEMBL24277978 0.75 TSHR (0.49) MMP12MMP13TSHRALDH1A1ATM
SCHEMBL9609749 0.74 CA1 (0.36) TSHRALDH1A1HTTRAB9ASMN1; SMN2
SCHEMBL5048243 0.73 TSHR (0.54) MMP12MMP13TSHRALDH1A1ATM
SCHEMBL9609714 0.73 HTT (0.43) TSHRALDH1A1ATMNPSR1GPR84
SCHEMBL9609745 0.72 CASR (0.37) ALDH1A1MAPK1SMN1; SMN2
SCHEMBL13029161 0.72 CA1 (0.37) TSHRALDH1A1MAPK1PRMT5WDR77
SCHEMBL9609709 0.69 NPC1 (0.41) TSHRALDH1A1ATMNPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L MMP12 4094/4885MMP13 3743/4885TSHR 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.