Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 15/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612005 | 0.85 | TRPV4 (0.55) | TRPV4CYP11B2CYP11B1 | |
| SCHEMBL22225479 | 0.78 | TRPV4 (0.48) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 | |
| SCHEMBL12873266 | 0.78 | GRM5 (0.34) | FFAR1FFAR4 | |
| SCHEMBL9293782 | 0.77 | CYP11B1 (0.50) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 | |
| SCHEMBL6864959 | 0.77 | TRPV4 (0.47) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 | |
| SCHEMBL7851781 | 0.74 | TRPV4 (0.45) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 | |
| SCHEMBL9293905 | 0.74 | TRPV4 (0.45) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 | |
| SCHEMBL1797379 | 0.73 | TRPV4 (0.59) | TRPV4CYP11B2CYP11B1EGLN2 | |
| SCHEMBL13657794 | 0.73 | CYP11B1 (0.53) | TRPV4CYP11B2CYP11B1 | |
| SCHEMBL9293042 | 0.73 | CYP2A6 (0.52) | TRPV4CYP11B2CYP11B1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169208-B2 | Aromatic and aromatic/heteroaromatic molecular structures with controllable electron conducting properties | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20120135249-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
| US-20110024691-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-03 | — | — | US | disclosed |
| US-7638632-B2 | 4-Ethynyl (1,2-dicyanobenzene)-4'-Ethynylphenyl-1(4,5-dicyanobenzene); 1,4-Bis(4-pyridyl)butadiyne; 4-ethynyl(pyridine)-4'-ethynylnaphthalene-1-pyridine; self-assembled mono-, multilayers/ supramolecular objects; three-terminal devices; logic switches;nanoelectronic ; computers; wires; dielectrics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-29 | — | — | US | disclosed |
| US-20090270627-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | FRENCH ROGER HARQUAIL | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135249-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | AHR, TYR, ARNT | TRPV4 67/4885CYP11B2 466/4885CYP11B1 622/4885 |
| US-20110024691-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | AHR, TYR, ARNT | TRPV4 67/4885CYP11B2 466/4885CYP11B1 622/4885 |
| US-20090270627-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | AHR, TYR, ARNT | TRPV4 67/4885CYP11B2 466/4885CYP11B1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.