SCHEMBL9610063

SCHEMBL9610063

CNC(=O)c1cc(C(C)(C(F)(F)F)C(F)(F)F)ccc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SORT1 Q99523 14/20 0.48
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
USP2 O75604 1/20 0.42
CYP2C19 P33261 1/20 0.42
NR1H4 Q96RI1 2/20 0.42
EPHX2 P34913 1/20 0.42
HTT P42858 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194874 0.84 TDP1 (0.64) SORT1TDP1NR1H4EPHX2
SCHEMBL22954898 0.80 SORT1 (0.42) SORT1TDP1KDM4EALDH1A1HPGD
SCHEMBL15695614 0.79 SORT1 (0.44) SORT1TDP1ALDH1A1NR1H4EPHX2
SCHEMBL15479584 0.78 SORT1 (0.44) SORT1TDP1KDM4EALDH1A1HPGD
SCHEMBL12972459 0.77 SORT1 (0.40) SORT1TDP1KDM4EALDH1A1HPGD
SCHEMBL7457551 0.75 CFTR (0.49) SORT1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL15887766 0.74 CA12 (0.41) SORT1TDP1KDM4EALDH1A1HTT
SCHEMBL28778686 0.74 TDP1 (0.50) SORT1TDP1KDM4EALDH1A1HPGD
SCHEMBL5178428 0.74 TDP1 (0.50) SORT1TDP1KDM4EALDH1A1HPGD
SCHEMBL460066 0.73 KDM4E (0.69) SORT1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120135251-A1 PHOTOSENSITIVE POLYIMIDE HAVING SILICON MODIFIED GROUP, ADHESIVE COMPOSITION AND SEMICONDUCTOR PACKAGE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-31 US disclosed