SCHEMBL9610345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9610348	0.86	APEX1 (0.36)	ALDH1A1MAPTAPEX1ELANEITGA4
	SCHEMBL9610343	0.86	TSHR (0.36)	APEX1ELANEPDK2TSHR
	SCHEMBL9610347	0.85	APEX1 (0.35)	ALDH1A1MAPTAPEX1ELANEITGA4
	SCHEMBL9610349	0.83	APEX1 (0.33)	ALDH1A1MAPTAPEX1ELANEITGA4
	SCHEMBL9610539	0.81	ELANE (0.39)	ALDH1A1MAPTELANEKDM4EL3MBTL1
	SCHEMBL9610566	0.81	ELANE (0.33)	ALDH1A1MAPTAPEX1ELANEMEN1
	SCHEMBL9610327	0.80	ELANE (0.39)	ALDH1A1MAPTAPEX1ELANEITGA4
	SCHEMBL20306518	0.80	PDK2 (0.35)	ALDH1A1MAPTSMN1; SMN2APEX1KDM4E
	SCHEMBL9610581	0.80	ELANE (0.33)	ALDH1A1MAPTAPEX1ELANETSHR
	SCHEMBL9610462	0.78	TDP1 (0.34)	MAPTELANEMEN1KMT2APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.