Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PLA2R1 | Q13018 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Macrocarpal H SCHEMBL30426500 | 1.00 | PTPN1 (0.44) | PTPN1TRPA1PLA2R1 | |
| Macrocarpal H SCHEMBL96107 | 1.00 | PTPN1 (0.44) | PTPN1TRPA1PLA2R1 | |
| SCHEMBL14142875 | 0.88 | TRPA1 (0.43) | PTPN1TRPA1PLA2R1 | |
| Macrocarpal I SCHEMBL134874 | 0.81 | PTPN1 (0.43) | PTPN1PLA2R1 | |
| Macrocarpal J SCHEMBL96425 | 0.81 | PTPN1 (0.43) | PTPN1PLA2R1 | |
| Macrocarpal I SCHEMBL29756964 | 0.81 | PTPN1 (0.43) | PTPN1PLA2R1 | |
| SCHEMBL12906575 | 0.73 | PTPN1 (0.52) | PTPN1PLA2R1 | |
| SCHEMBL12906565 | 0.73 | PTPN1 (0.52) | PTPN1PLA2R1 | |
| SCHEMBL2888923 | 0.67 | PTPN1 (0.60) | PTPN1PLA2R1 | |
| SCHEMBL3716275 | 0.67 | PTPN1 (0.60) | PTPN1PLA2R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058172-A1 | PLANT EXTRACTS FOR USE IN BRAIN MODULATION | INTERMED DISCOVERY GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20120058172-A1 | PLANT EXTRACTS FOR USE IN BRAIN MODULATION | INTERMED DISCOVERY GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| WO-2008074420-A1 | PLANTS EXTRACTS FOR USE IN BRAIN MODULATION | INTERMED DISCOVERY GMBH (DE) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058172-A1 | PLANT EXTRACTS FOR USE IN BRAIN MODULATION | PYGB, FABP7, LANCL1 | PTPN1 3808/4885TRPA1 3242/4885PLA2R1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.