Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029899 | 0.79 | ECE2 (0.46) | ECE2SHMT2NPC1RAB9AMET | |
| SCHEMBL13573864 | 0.77 | ECE2 (0.45) | ECE2SHMT2NPC1RAB9AMET | |
| SCHEMBL3820906 | 0.77 | ECE2 (0.45) | ECE2SHMT2NPC1RAB9AMET | |
| SCHEMBL31367022 | 0.77 | LOXL2 (0.47) | ECE2SHMT2 | |
| SCHEMBL843959 | 0.77 | ECE2 (0.45) | ECE2SHMT2NPC1RAB9AMET | |
| SCHEMBL2056360 | 0.77 | NOS3 (0.52) | ECE2SHMT2NPC1RAB9AMAPT | |
| SCHEMBL2860410 | 0.77 | LOXL2 (0.47) | ECE2SHMT2 | |
| SCHEMBL6763074 | 0.77 | ECE2 (0.49) | ECE2SHMT2NPC1RAB9AHDAC3 | |
| Hydrochloric Acid SCHEMBL28952754 | 0.76 | LOXL2 (0.45) | ECE2SHMT2GAAPKM | |
| Hydrochloric Acid SCHEMBL9196645 | 0.76 | ECE2 (0.47) | ECE2SHMT2NPC1RAB9AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |