Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26297792 | 0.82 | ALDH1A1 (0.43) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL30328203 | 0.79 | KMT2A (0.46) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL9611671 | 0.77 | KMT2A (0.66) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL9611679 | 0.77 | MAPT (0.52) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL13916705 | 0.77 | ALDH1A1 (0.57) | PI4KAPI4K2BPI4K2API4KBBACE1 | |
| SCHEMBL30785418 | 0.77 | ADORA2A (0.49) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL29202375 | 0.77 | ADORA2A (0.46) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL29202412 | 0.77 | ADORA2A (0.46) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL27158408 | 0.77 | ADORA2A (0.49) | ADORA2AADORA2BADORA3ADORA1PI4KA | |
| SCHEMBL1462732 | 0.73 | KMT2A (0.50) | ADORA2AADORA2BADORA3BACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126943-B2 | Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-9126943-B2 | Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | H1-2, L1CAM, H1-0 | ADORA2A 3716/4885ADORA2B 2711/4885ADORA3 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.