Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462732 | 0.79 | KMT2A (0.50) | KMT2ABACE1MEN1TLR7ALDH1A1 | |
| SCHEMBL12326600 | 0.79 | BACE1 (1.00) | KMT2ABACE1MEN1RAB9ANPC1 | |
| SCHEMBL2750728 | 0.78 | BACE1 (0.46) | KMT2ABACE1RAB9ANPC1BRD4 | |
| SCHEMBL10247452 | 0.78 | KMT2A (0.64) | KMT2ABACE1MEN1RAB9ANPC1 | |
| SCHEMBL9611675 | 0.77 | ADORA2A (0.50) | KMT2ABACE1ATMMEN1RAB9A | |
| SCHEMBL9611677 | 0.77 | ATM (0.53) | KMT2ABACE1ATMMEN1RAB9A | |
| SCHEMBL14947869 | 0.75 | KMT2A (0.59) | KMT2ABACE1MEN1RAB9ANPC1 | |
| SCHEMBL7549940 | 0.74 | ALDH1A1 (0.46) | KMT2ABACE1MEN1RAB9ANPC1 | |
| SCHEMBL18225432 | 0.74 | KDM4E (0.61) | KMT2ABACE1MEN1RAB9ANPC1 | |
| SCHEMBL1701244 | 0.74 | SMN1; SMN2 (0.52) | KMT2ABACE1RAB9ANPC1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126943-B2 | Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-9126943-B2 | Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132899-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | H1-2, L1CAM, H1-0 | KMT2A 1153/4885BACE1 1070/4885ATM 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.