Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12123735 | 0.84 | BCL2L1 (0.59) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL7209477 | 0.81 | BCL2L1 (0.74) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL29746765 | 0.78 | BCL2L1 (0.59) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL21847973 | 0.78 | BCL2L1 (0.59) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL7636919 | 0.77 | BCL2L1 (0.54) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL6334117 | 0.77 | BCL2L1 (0.62) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL7639982 | 0.76 | BCL2L1 (0.72) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL9048628 | 0.76 | RAB9A (0.60) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL3631856 | 0.76 | RAB9A (0.56) | RAB9ABCL2L1HDAC3HDAC1HDAC2 | |
| SCHEMBL8958420 | 0.75 | BCL2L1 (0.65) | RAB9ABCL2L1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068702-A1 | BENZO 5-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS AND PREPARATION METHODS THEREOF | 中国医学科学院医药生物技术研究所 (CN) | 2012-05-31 | — | — | WO | disclosed |