SCHEMBL9612673

SCHEMBL9612673

CC(=O)c1cc2cc(C(=O)O)ccc2s1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 8/20 0.65
DYRK1B Q9Y463 8/20 0.65
CLK1 P49759 7/20 0.65
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HDAC1 Q13547 4/20 0.48
BCL2L1 Q07817 1/20 0.47
HSD17B1 P14061 2/20 0.44
TBXAS1 P24557 1/20 0.44
GPR35 Q9HC97 1/20 0.43
LMNA P02545 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4082326 0.87 BCL2L1 (0.61) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL9612781 0.86 CLK1 (0.51) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL15697575 0.86 BCL2L1 (0.56) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL9612670 0.82 CLK1 (0.59) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL12663051 0.82 HDAC1 (0.55) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL30659843 0.81 DYRK1A (0.58) DYRK1ADYRK1BCLK1SMN1; SMN2HDAC1
SCHEMBL23832902 0.80 NPC1 (0.44) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL6299629 0.79 SMN1; SMN2 (0.57) DYRK1ADYRK1BCLK1NPC1RAB9A
SCHEMBL4161689 0.79 DYRK1A (1.00) DYRK1ADYRK1BCLK1SMN1; SMN2BCL2L1
SCHEMBL6840172 0.79 DYRK1A (0.69) DYRK1ADYRK1BCLK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103044390-B Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2015-02-25 CN claimed
CN-101906093-B Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST MEDICINAL BIOTECHNOLOGY 2013-07-10 CN claimed
CN-103050628-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN claimed
CN-103050629-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN claimed
CN-103044390-A Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN claimed
CN-103044389-A Compound used as active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN claimed
CN-102997991-A Ultraviolet detection device LIYANG PRODUCTIVITY PROMOTION CT 2013-03-27 CN claimed
CN-102969450-A Ultraviolet detector LIYANG CITY PRODUCTIVITY PROMOTION CT 2013-03-13 CN claimed
CN-101906093-A Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES 2010-12-08 CN claimed
CN-102969450-B A kind of ultraviolet detector 溧阳市生产力促进中心 2016-06-08 CN disclosed
CN-103050629-B A kind of manufacture method of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CENTER (CN) 2016-04-06 CN disclosed
CN-102997991-B A kind of ultraviolet detector LIYANG CITY PRODUCTIVITY PROMOTION CENTER (CN) 2016-01-06 CN disclosed
CN-103044390-B Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2015-02-25 CN disclosed
CN-101906093-B Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST MEDICINAL BIOTECHNOLOGY 2013-07-10 CN disclosed
CN-103050629-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103044389-A Compound used as active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-102997991-A Ultraviolet detection device LIYANG PRODUCTIVITY PROMOTION CT 2013-03-27 CN disclosed
CN-102969450-A Ultraviolet detector LIYANG CITY PRODUCTIVITY PROMOTION CT 2013-03-13 CN disclosed
WO-2012068702-A1 BENZO 5-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS AND PREPARATION METHODS THEREOF 中国医学科学院医药生物技术研究所 (CN) 2012-05-31 WO disclosed
CN-101906093-A Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES 2010-12-08 CN disclosed