Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250577 | 0.87 | BCL2L1 (0.61) | HDAC1CA2BCL2L1RAB9ANPC1 | |
| SCHEMBL9612673 | 0.86 | DYRK1A (0.65) | CLK1DYRK1ADYRK1BHDAC1BCL2L1 | |
| SCHEMBL8260519 | 0.86 | CA2 (0.56) | CLK1DYRK1ADYRK1BHDAC1CA2 | |
| SCHEMBL9612674 | 0.82 | HDAC1 (0.76) | CLK1DYRK1ADYRK1BHDAC1CA2 | |
| SCHEMBL1886146 | 0.82 | HDAC1 (0.67) | HDAC1CA2BCL2L1RAB9ANPC1 | |
| SCHEMBL13709557 | 0.80 | C1S (0.50) | HDAC1CA2BCL2L1RAB9ANPC1 | |
| SCHEMBL3966584 | 0.79 | RAB9A (0.53) | HDAC1CA2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15961987 | 0.79 | DYRK1A (0.74) | CLK1DYRK1ADYRK1BHDAC1CA2 | |
| SCHEMBL191958 | 0.79 | HDAC1 (0.51) | HDAC1CA2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8905597 | 0.77 | DYRK1A (0.53) | CLK1DYRK1ADYRK1BHDAC1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044390-B | Manufacturing method of active layer of ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2015-02-25 | — | — | CN | claimed |
| CN-101906093-B | Benzo five-membered unsaturated heterocycle compound and preparation method thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-07-10 | — | — | CN | claimed |
| CN-103044390-A | Manufacturing method of active layer of ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2013-04-17 | — | — | CN | claimed |
| CN-103044389-A | Compound used as active layer of ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2013-04-17 | — | — | CN | claimed |
| CN-103050629-A | Method for producing ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2013-04-17 | — | — | CN | claimed |
| CN-103050628-A | Method for producing ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2013-04-17 | — | — | CN | claimed |
| CN-102997991-A | Ultraviolet detection device | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | claimed |
| CN-102969450-A | Ultraviolet detector | LIYANG CITY PRODUCTIVITY PROMOTION CT | 2013-03-13 | — | — | CN | claimed |
| CN-101906093-A | Benzo five-membered unsaturated heterocycle compound and preparation method thereof | INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES | 2010-12-08 | — | — | CN | claimed |
| CN-102969450-B | A kind of ultraviolet detector | 溧阳市生产力促进中心 | 2016-06-08 | — | — | CN | disclosed |
| CN-103050629-B | A kind of manufacture method of ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CENTER (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-102997991-B | A kind of ultraviolet detector | LIYANG CITY PRODUCTIVITY PROMOTION CENTER (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-103044390-B | Manufacturing method of active layer of ultraviolet detector | LIYANG PRODUCTIVITY PROMOTION CT | 2015-02-25 | — | — | CN | disclosed |
| CN-101906093-B | Benzo five-membered unsaturated heterocycle compound and preparation method thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-07-10 | — | — | CN | disclosed |
| CN-102997991-A | Ultraviolet detection device | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | disclosed |
| CN-102969450-A | Ultraviolet detector | LIYANG CITY PRODUCTIVITY PROMOTION CT | 2013-03-13 | — | — | CN | disclosed |
| WO-2012068702-A1 | BENZO 5-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS AND PREPARATION METHODS THEREOF | 中国医学科学院医药生物技术研究所 (CN) | 2012-05-31 | — | — | WO | disclosed |
| CN-101906093-A | Benzo five-membered unsaturated heterocycle compound and preparation method thereof | INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES | 2010-12-08 | — | — | CN | disclosed |
| US-7834034-B2 | Benzothiophene derivatives | MERCK SHARP & DOHME CORP. (US) | 2010-11-16 | — | — | US | disclosed |
| US-20090082308-A1 | Benzothiophene derivatives | MERCK SHARP & DOHME LLC | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082308-A1 | Benzothiophene derivatives | BRDT, HDAC5, BRPF3 | CLK1 4160/4885DYRK1A 2841/4885DYRK1B 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.