SCHEMBL4082326

SCHEMBL4082326

O=C(O)c1ccc2sc(C(=O)O)cc2c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.61
GPR35 Q9HC97 3/20 0.56
DYRK1A Q13627 7/20 0.53
DYRK1B Q9Y463 7/20 0.53
CLK1 P49759 6/20 0.53
HDAC1 Q13547 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TBXAS1 P24557 2/20 0.47
HSD17B1 P14061 2/20 0.44
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612673 0.87 DYRK1A (0.65) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL15697575 0.87 BCL2L1 (0.56) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL15697586 0.87 BCL2L1 (0.56) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL8250577 0.85 BCL2L1 (0.61) BCL2L1GPR35HDAC1SMN1; SMN2NPC1
SCHEMBL1883961 0.84 HDAC1 (0.60) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL15697578 0.84 DYRK1A (0.63) BCL2L1GPR35DYRK1ADYRK1BCLK1
Beta-Naphtoic Acid SCHEMBL27589159 0.83 BCL2L1 (0.75) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL12663051 0.83 HDAC1 (0.55) BCL2L1DYRK1ADYRK1BCLK1HDAC1
SCHEMBL20787972 0.83 LMNA (0.57) BCL2L1GPR35DYRK1ADYRK1BCLK1
SCHEMBL15697491 0.83 BCL2L1 (0.51) BCL2L1GPR35DYRK1ADYRK1BCLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300372-B Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2024-03-15 CN claimed
CN-112300372-A Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2021-02-02 CN claimed
CN-120349523-A Iron-based porous coordination polymer and preparation method and application thereof 德州学院 2025-07-22 CN disclosed
CN-112300372-B Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2024-03-15 CN disclosed
CN-112300372-B Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2024-03-15 CN disclosed
CN-112300372-A Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2021-02-02 CN disclosed
CN-112300372-A Preparation and application of sulfur-containing copolyester partially derived from biomass 武汉科技大学 2021-02-02 CN disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
WO-2014073623-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed
EP-1677731-A4 THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES ATON PHARMA INC (US) 2009-05-06 EP disclosed
EP-1677731-A2 THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES Aton Pharma, Inc. (US) 2006-07-12 EP disclosed
WO-2005034880-A2 THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES ATON PHARMA, INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B BCL2L1 2137/4885GPR35 3997/4885DYRK1A 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.