SCHEMBL9612794

SCHEMBL9612794

CNc1ccc2c(c1)C(=O)/C(=C1\Nc3ccc(NC)cc3C1=O)N2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ TGM2 P21980 5/20 0.42
▸ CES1 P23141 3/20 0.42
▸ ALDH1A1 P00352 2/20 0.39
▸ PDPK1 O15530 2/20 0.36
▸ MAOA P21397 2/20 0.36
▸ MAOB P27338 2/20 0.36
▸ CASP3 P42574 2/20 0.36
▸ ROS1 P08922 1/20 0.35
▸ CDK5 Q00535 1/20 0.35
▸ ACVR1 Q04771 1/20 0.35
▸ LRRK2 Q5S007 1/20 0.35
▸ CA12 O43570 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ EGFR P00533 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13203153 0.82 MAPT (0.39) APPMAPTTGM2CES1BRD4
SCHEMBL19006416 0.75 ROS1 (0.55) MAPTTGM2CES1ALDH1A1PDPK1
SCHEMBL19855793 0.75 CES1 (0.71) MAPTTGM2CES1MAOAMAOB
SCHEMBL5383487 0.73 APP (0.44) APPMAPTTGM2CES1ALDH1A1
SCHEMBL10282762 0.72 KDM4E (0.59) ALDH1A1CASP3EGFRKDM4EGLA
SCHEMBL17918988 0.71 MEN1 (0.53) MAPTALDH1A1MAOA
SCHEMBL28881913 0.71 TGM2 (0.71) TGM2CES1CDK5LRRK2CA1
SCHEMBL11920848 0.71 TGM2 (0.71) TGM2CES1CDK5LRRK2CA1
SCHEMBL21708143 0.71 MAOB (0.45) TGM2CES1MAOAMAOBLRRK2
SCHEMBL4886879 0.71 TGM2 (0.41) TGM2CES1ALDH1A1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1158321-B1 Dichroic light polarizers with non-periodic arrangement of different polarizing elements NITTO DENKO CORP (JP) 2012-05-30 — — EP disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 — — US disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 — — US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 — — US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 — — US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 — — US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 — — US disclosed
EP-1158320-B1 Dichroic light polarizers NITTO DENKO CORP (JP) 2008-08-06 — — EP disclosed
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